, Kina (S)-1-Boc-3-hydroxypiperidine hana a me ka hale hana |Hengkang
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(S)-1-Boc-3-hydroxypiperidine

ʻO ka wehewehe pōkole:

kiʻi4

CAS: 143900-44-1

MF: C10H19NO3

MW: 201.26


Huahana Huahana

Huahana Huahana

Māhele Huahana

ʻO ChiralReagents; Piperidines; Heterocycles; Intermediates & Fine Chemical; Laʻau Laʻau; Anticancer

Nā huaʻōlelo like

(S)-1-Boc-3-Hydroxypiperidine

(S)-1-N-BOC-3-HYDROXY-PIPERIDINE

(S)-3-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(S)-3-HYDROXY-1-(TERT-BUTOXYCARBONYL)PIPERIDINE

(S)-1-BOC-3-PIPERIDINOL

(S)-N-(TERT-BUTOXYCARBONYL)-3-HYDROXYPIPERIDINE HYDROCHLORIDE

(S)-N-BOC-3-HYDROXY PIPERIDINE

(S)-TERT BUTYL-3-HYDROXYPIPERIDINE-1-CARBOXYLATE

(S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine

S-1-Boc-3-hydroxypiperidine

(3S)-hydroxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

(S)-3,5-DifluoroMandelic acid

(S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate

(S)-tert-Butyl-3-hydroxypiperidine-1-carboxylate tert- butyl

(3S)-3-hydroxy piperidine-1-carboxylate tert-butyl

(S)-3-hydroxypiperidine-1-carboxylate

(3S)-3-Hydroxypiperidine, N-BOC i pale ʻia

(S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine

Na Waiwai Kemika

Ka helu hehee: 34-40 °C

Puni paila: 292.3±33.0 °C (Wānana ʻia)

Māmā: 1.107±0.06 g/cm3 (Wānana ʻia)

Fp: 110 °C

ka mahana mālama: E mālama i kahi pōʻeleʻele, Hoʻopaʻa ʻia i kahi maloʻo, Ke ana wela o ka lumi

hiki ke hoʻoheheʻe ʻia: Soluble in methanol.

Pka: 14.74±0.20(Wānana ʻia)

ʻAno: Pahu a i ʻole Crystalline Powder

Kala: Keʻokeʻo a ʻeleʻele

hana opua: [α]22/D +10.0°, c = 1 i loko o ka chloroform

InChIKey: UIJXHKXIOCDSEB-QMMMGPOBSA-N

ʻIke pilikia

1 Ka hoʻokaʻawale ʻana o ka mea a i ʻole ka hui ʻana

ʻO ka ʻili ʻili, Māhele 2

ʻO ka ukiuki maka, Māhele 2

ʻO ka ʻawaʻawa o ke kino i hoʻopaʻa ʻia - ʻike hoʻokahi, Māhele 3

2 mau mea lepili GHS, me nā ʻōlelo hoʻomalu

Piktogram(mau)  kiʻi5
ʻŌlelo hōʻailona ʻŌlelo aʻo
ʻŌlelo (mau) pōʻino H315 Hoʻopilikia i ka ʻili

H319 Hoʻopilikia i ka maka

H335 Hiki ke hoʻoulu i ka hanu

ʻŌlelo kiaʻi
Kāohi P264 Holoi ... ma hope o ka lawelawe ʻana.

P280 E ʻaʻahu i nā mīkina lima pale / lole pale / pale maka / pale maka / pale lohe / ...

P261 Hōʻalo i ka hanu ʻana i ka lepo/fume/gas/noe/vapours/spray.

P271 E hoʻohana ma waho wale nō a i ʻole ma kahi ea maikaʻi.

Pane P302+P352 INA MA KA ILI: Holoi me ka wai nui/...

P321 Lapaʻau kūikawā (nānā ... ma kēia lepili).

P332+P317 Inā ʻeha ka ʻili: E kiʻi i ke kōkua olakino.

P362+P364 Wehe i nā lole i haumia a holoi ma mua o ka hoʻohana hou ʻana.

P305+P351+P338 INA I KA MAKA: Holoi akahele me ka wai no kekahi mau minuke.Wehe i nā leka pili, inā aia a maʻalahi ke hana.E hoʻomau i ka holoi ʻana.

P304+P340 INA INHALED: Wehe i ke kanaka i ka ea hou a noho mālie no ka hanu ʻana.

P319 E kiʻi i ke kōkua kino inā pilikia ʻoe.

Waihona P403+P233 E kūʻai i loko o kahi ea.Paʻa paʻa ka ipu.

Paʻa ka hale kūʻai P405.

Holoi P501 E hoʻolei i nā mea i loko / pahu i kahi lapaʻau kūpono a me kahi hale hoʻolei e like me nā kānāwai a me nā lula pili, a me nā ʻano huahana i ka manawa o ka hoʻokuʻu ʻia.

3 Nā pōʻino ʻē aʻe i hopena ʻole i ka hoʻokaʻawale ʻana

ʻaʻohe ʻikepili i loaʻa

Huahana Huahana

ʻAno/kala Paʻa keʻokeʻo a keʻokeʻo
Hiki ke agglomerate ma hope o ka mālama ʻana i nā manawa lōʻihi
ʻIkepili (IR) Kūlike
Hōʻike (HPLC w/w) 97.0%-103.0%
Maʻemaʻe kemika (wahi GC) ﹦ 99.0%
Maʻemaʻe haumia (GC w/w) 3-Hydroxypiperidine﹦ 0.1%
3-Hydroxypyridine﹦ 0.20% ʻAʻole ʻike ʻia
1-Boc-3-piperidone﹦ 0.10% ʻAʻole ʻike ʻia
1-Boc-4-hydroxypiperidine﹦ 0.10% ʻAʻole ʻike ʻia
1.96RRT﹦ 0.2% ʻAʻole ʻike ʻia
ʻO kēlā me kēia haumia ʻaʻole i hōʻike ʻia﹦ 0.08% 0.01%
ʻO ka maʻemaʻe Chiral (wahi HPLC) ﹦ 99.5%
Methanol(GC) ﹦ 50ppm
Ethanol(GC) ﹦ 50ppm
DCM(GC) ﹦ 500ppm
Wai (KF vol w/w) ﹦ 0.5%

ʻO kā mākou pono

1: Ua ʻike kā mākou hale hana i ka ʻoihana kūʻai nui mai ka makahiki 2012, ʻoi aku ka nui o nā kūʻai makahiki ma mua o 20tons.
2 ʻO ia ka mea hoʻolako kūpono no ka hui lāʻau patent o Ibrutinib.
3 ʻOi aku ka maikaʻi o ka huahana: Assay: 97.0%-103.0%
Maʻemaʻe kemika (wahi GC): ﹦ 99.0%
ʻO nā mea haumia ʻole i hōʻike ʻia﹤ ﹦ 0.08%
ʻO ka maʻemaʻe chiral (wahi HPLC): ﹥ ﹦ 99.5%
4 Hana ʻia ia e ke ʻano hoʻonā Kemika.
5 Ua hōʻoia ʻia nā ʻano hoʻāʻo a pau.
6 Hoʻokahi hale hana hoʻolaʻa no ka hana ʻana.


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