5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine

ʻO ka wehewehe pōkole:

CAS: 330786-24-8

MF: C₁₇H₁₃N₅O

MW: 303.32

EINECS: 810-090-0

Nā Māhele Huahana: Ibrutinib;ʻAi maʻi maʻi

E hoʻouna i ka leka uila iā mākou Loaʻa i nā Laʻana

Huahana Huahana

Nā huaʻōlelo like

5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine

4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine

3-(4-phenoxy-phenyl)-1(2)H-pyrazole

3-(4-phenoxyphenyl)-1H-pyrazole

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

3-[4-phenoxyphenyl]pyrazole

Ibrutinib N-2

3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-D]pyrimidine-4-amine

1H-Pyrazolo[3,4-d]pyrimidin-4-amine,

Na waiwai kino-kimika

ʻĀpana Molekala	C5H8O3
Molar Mass	116.115 g/mol
ʻO ka mānoanoa	1.262g/cm³
Lae Boling	243.2°C ma 760 mmHg
Lae Flash	113.2°C
Puʻupuʻu mahu	0.0107mmHg ma 25°C
Hōʻike Hōʻike	1.48

Na Waiwai Kemika

Density: 1.380±0.06 g/cm3 (20 ºC 760 Torr),

Sʻoluʻolu: ʻAʻole hiki ke hoʻonā (1.2E-3 g/L) (25 ºC),

PSA : 89.71000

LogP: 3.97560

ʻIke palekana

2.1 Hoʻokaʻawale ʻana o ka mea a i ʻole ka hui ʻana

ʻona ʻino - Māhele 4, waha

2.2 Nā mea lepili GHS, me nā ʻōlelo hoʻomalu

Piktogram(mau)
ʻŌlelo hōʻailona	ʻŌlelo aʻo
ʻŌlelo (mau) pōʻino	H302 Poino ke aleia
ʻŌlelo kiaʻi
Kāohi	P264 Holoi ... ma hope o ka lawelawe ʻana. P270 Mai ʻai, inu a puhi paha i ka wā e hoʻohana ai i kēia huahana.
Pane	P301+P317 INA ʻAle: E kiʻi i ke kōkua kino. P330 Holoi waha.
Waihona	ʻaʻohe
Holoi	P501 E hoʻolei i nā mea i loko / pahu i kahi lapaʻau kūpono a me kahi hale hoʻolei e like me nā kānāwai a me nā lula pili, a me nā ʻano huahana i ka manawa o ka hoʻokuʻu ʻia.

Nā Kūlana Huahana

ʻAno/kala: ʻAhinahina Māmā, keʻokeʻo a i ʻole ʻulaʻula ʻulaʻula
ʻIke: 98.0%~102.0%
moʻolelo haumia:
IBR-4-m-OPh NMT 0.10%
IBR-4-o-OPh NMT 0.10%
NMT ʻē aʻe 0.20%
Huina haumia NMT 1.0%
ʻO ka hoʻomaʻemaʻe kemika (ʻāpana HPLC) ≥ 99.0%
LOD(%): ≤1.0%

ʻO kā mākou pono

1 Loaʻa iā mākou ka laikini hoʻokuʻu aku e hana iā ʻoe me ka hale hana i loaʻa pololei.
2 No nā waiwai weliweli hiki iā mākou ke hana i ka palapala hoʻouna palekana no ʻoe.
3 Ua ʻae ʻia ka hoʻāʻo ʻana o ka ʻaoʻao ʻekolu.
4 Hiki ke hāʻawi ʻia ka hāʻawi mua ʻana no ka manuahi.

Mua: (R)-(+)-2-Tetrahydrofuroic acid

Aʻe: (S)-1-Boc-3-hydroxypiperidine